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By Darrell Miller
L-arginine is one of the amino acids most widespread in nature, and involved in varied tasks of biological significance in heterotrophs such as human beings. The scientific community is convinced that the body produces the right amounts of L-arginine under normal circumstances, but also points out that individuals with unhealthy levels of L-arginine must get this chemical compound from their diets, infants included. The presence of L-arginine in the human body must amount to concentrations sufficient to support bodily functions such as healthy circulation and blood flow.
Poor nutrition is associated with low levels of L-arginine, which in turn has been associated with most cases of high blood pressure. Blood pressure is one of the most important measures of physiological functions adopted by modern day medicine, and more often than not pertinent to the assessment of human health and medical conditions. While there are no identifiable causes of high blood pressure, the use of L-arginine in treatment of cardiovascular diseases and hypertension has been common place.
Endothelium-Derived Relaxing Factor
What are the principles that led to the utilization of L-arginine against diseases of the circulatory system? Endothelial tissues are a thin lining of cells on the inner surface of blood vessels exposed to the inside space where blood flows and lying just next to the smooth muscle cells that do most of the pumping. These tissues are found everywhere in the circulatory system, including the heart and even the smallest of all blood vessels, and are responsible for stimulating the smooth muscle tissues beneath them to perform mechanisms that decrease the randomness of blood flow.
The endothelium releases a mixture of substances referred to as EDRF, the abbreviated form of endothelium-derived relaxing factor, resulting in the vasodilation of the smooth muscle tissues of the blood vessels. EDRF is in fact nitric oxide that plays the key role of a biological messenger not only in human beings, but in all animals with backbones and spinal columns. With or without a combination of compounds, nitric oxide induces the blood vessels to widen as the smooth muscle tissues relax, promoting an increase in the flow of blood and, of course, a decrease in blood pressure.
L-Arginine and Nitric Oxide
The efficacy of EDRF in connection with its mechanisms that relax the smooth muscle tissues has been attributed to nitric oxide, in itself active in other animals in the same manner, and the production of nitric oxide in the human body is governed by the availability of the bioactive compound L-arginine. EDRF is an endogenous substance that is synthesized inside the body, but L-arginine can be absorbed from an outside source.
Individuals who dont meet their nutritional needs have been reported to have low levels of L-arginine, and, if suffering from cardiovascular diseases or hypertension, their endothelial cells do not respond effectively to the chaos inside the blood vessels. L-arginine in supplements is a significant precursors of nitric oxide used as EDRF by the endothelium, promoting an overall circulatory health.
L-arginine is available in capsule, tablet, powder, and liquid forms. Look for quality L-arginine at your local or internet vitamin store.
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